Specifically, our laboratory focuses on
- the postsynaptic molecular mechanisms of plasticity at GABAergic synapses;
- the mechanisms of interplay between excitation and inhibition at single synapse level;
- the role of inhibitory synaptic plasticity in visual learning in vivo.
We study synaptic function using an array of cutting-edge imaging/optical techniques including Single Particle Tracking (SPT), optogenetics (Light-gated Glutamate Receptors), fast live confocal microscopy and diffraction limited UV laser photolysis of caged neurotransmitters, as well as electrophysiology, molecular biology and in vivo manipulations.